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Builders & open source

Joshua Meier

Co-founder and CEO, Chai Discovery

Joshua Meier is a co-founder and the CEO of Chai Discovery, a company that builds AI models for designing molecules, including the open Chai-1 structure prediction model and the Chai-2 antibody design model. Meier founded Chai Discovery in 2024 with Jack Dent, Matthew McPartlon and Jacques Boitreaud.123

At a glance

Current role
Co-founder and CEO
Sector
Company
Work listed
2
Sources cited
5
Profile reviewed

Chai Discovery

Meier co-founded Chai Discovery in 2024 with Jack Dent, Matthew McPartlon and Jacques Boitreaud; the company describes its team's backgrounds as spanning OpenAI, Meta FAIR, Stripe, molecular design and academic research. Chai Discovery says it is building a computer-aided design suite for molecules.14

Chai's open chai-lab repository hosts Chai-1, described in the 2024 technical report "Chai-1: Decoding the molecular interactions of life", and cites a 2025 Chai-2 report on zero-shot antibody design.2

Products and projects

In November 2025 Chai published results on antibodies designed by Chai-2 against challenging targets, including tests of developability. In July 2026 Meier announced a collaboration with Novartis on AI-driven antibody discovery that gives Novartis access to Chai's newer models, including Chai-3.31

Work and contributions

  • Chai-1

    Co-founder and CEO of the company that released Chai-1, a model for predicting molecular structures described in a 2024 technical report credited to Chai Discovery.21

  • Chai-1 (weights used by chai_lab 0.6.1) Open weights

    Listed among the authors of the Chai-1 technical report on bioRxiv, which the Chai-1 model card cites.5

Timeline

  1. Co-founded Chai Discovery with Jack Dent, Matthew McPartlon and Jacques Boitreaud.1
  2. Chai Discovery released the Chai-1 technical report and open chai-lab code.2
  3. Chai Discovery published a research update on drug-like antibody design with Chai-2.3
  4. Announced, as CEO, a collaboration with Novartis on AI-driven antibody discovery.1

Where they work

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References

5 sources · profile reviewed Oct 21, 2026 · data updated Oct 22, 2026

  1. Chai Discovery announces collaboration with Novartis to advance AI-driven antibody discoveryChai Discovery · Announcement · published Jul 13, 2026 · accessed Oct 21, 2026 · reviewed Oct 21, 2026
  2. chaidiscovery/chai-lab README (Chai-1 and citations)Chai Discovery (GitHub repository) · Repository · accessed Oct 21, 2026 · reviewed Oct 21, 2026
  3. Drug-like antibody design against challenging targets with atomic precisionChai Discovery · Announcement · published Nov 19, 2025 · accessed Oct 21, 2026 · reviewed Oct 21, 2026
  4. Chai Discovery — homepageChai Discovery · Official page · accessed Oct 21, 2026 · reviewed Oct 21, 2026
  5. Chai-1: Decoding the molecular interactions of life (bioRxiv, doi:10.1101/2024.10.10.615955)bioRxiv · Paper · published Oct 11, 2024 · accessed Oct 22, 2026