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Portrait of Daphne Koller
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Daphne Koller

Founder & CEO, Board Member, insitro

  • Founder & CEO, Board Member, insitro1
  • Adjunct Professor, Computer Science (formerly the Rajeev Motwani Professor of computer science), Stanford University21

Daphne Koller is the founder and CEO of insitro, a machine learning-driven drug discovery and development company. Koller was the Rajeev Motwani Professor of computer science at Stanford University, on the faculty for 18 years, and remains an adjunct faculty member. Koller co-founded the online education platform Coursera, where Koller was co-CEO and president, co-founded the digital learning platform Engageli, and was formerly chief computing officer of Calico, an Alphabet company. Koller is listed as the instructor of the Probabilistic Graphical Models specialization offered by Stanford Online on Coursera.123

At a glance

Current roles
Founder & CEO, Board Member +1 more
Sector
Company
Education
Stanford
Work listed
1
Honors
12
Sources cited
4
Profile reviewed

Career

Daphne Koller spent 18 years on the computer science faculty at Stanford University, where Koller held the Rajeev Motwani Professorship and remains an adjunct faculty member. Koller co-founded the online learning platform Coursera, serving as co-CEO and president, and later co-founded Engageli, an interactive digital learning platform.1

Koller was formerly chief computing officer of Calico, an Alphabet company working in health, and founded insitro in 2018. insitro applies machine learning to drug discovery and development, and Koller leads it as CEO and serves on its board.14

Teaching and writing

Koller's research has appeared in venues ranging from Science, Cell and Nature Genetics to NeurIPS and ICML. Koller is listed as the instructor of the Probabilistic Graphical Models specialization that Stanford Online offers on Coursera, and Stanford recognized Koller's teaching with its Medal for Excellence in Fostering Undergraduate Research and a Bass University Fellowship in Undergraduate Education.13

Work and contributions

Timeline

  1. Received a Sloan Foundation Faculty Fellowship.1
  2. Received the IJCAI Computers and Thought Award.1
  3. Received the ACM Prize in Computing.1
  4. Founded insitro, a machine learning-driven drug discovery and development company.41
  5. Was inducted into the National Academy of Sciences.1

Other documented roles

Roles the sources document that are not confirmed as current.

  • Co-founder, co-CEO and president, Coursera1
  • Chief computing officer, Calico1

Honors and recognition

  • Sloan Foundation Faculty Fellowship · Alfred P. Sloan Foundation, 19961
  • ONR Young Investigator Award · Office of Naval Research, 19981
  • Presidential Early Career Award for Scientists and Engineers · U.S. Government, 19991
  • IJCAI Computers and Thought Award · International Joint Conferences on Artificial Intelligence, 20011
  • MacArthur Fellowship · John D. and Catherine T. MacArthur Foundation, 20041
  • AAAI Fellow · Association for the Advancement of Artificial Intelligence, 20041
  • ACM Prize in Computing · Association for Computing Machinery, 20081
  • Member, National Academy of Engineering · U.S. National Academy of Engineering, 20111
  • Fellow, American Academy of Arts and Sciences · American Academy of Arts and Sciences, 20141
  • ISCB Fellow · International Society for Computational Biology, 20171
  • ACM AAAI Allen Newell Award · Association for Computing Machinery and AAAI, 20191
  • Member, National Academy of Sciences · U.S. National Academy of Sciences, 20231

Where they work

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References

4 sources · profile reviewed Oct 21, 2026 · data updated Oct 21, 2026

  1. Daphne Koller — insitro leadershipinsitro · Official page · accessed Oct 21, 2026
  2. Daphne Koller — Stanford ProfilesStanford University · Official page · accessed Oct 13, 2026
  3. Probabilistic Graphical Models Specialization (Stanford Online)Coursera · Official page · accessed Oct 21, 2026
  4. insitro — Aboutinsitro · Official page · accessed Oct 21, 2026